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Posted by: | Posted on: November 18, 2020

WHO: Certain H1N1 cases may predict antiviral resistance

first_imgSep 25, 2009 (CIDRAP News) – While antiviral-resistant H1N1 influenza viruses remain rare, clinicians should watch for two particular kinds of H1N1 cases that seem more likely to give rise to viruses resistant to oseltamivir (Tamiflu), the World Health Organization (WHO) said today.So far, 28 oseltamivir-resistant viruses have been detected worldwide, the WHO said in today’s statement. Twelve of these were linked to use of the drug for postexposure prophylaxis, and 6 were in patients who had severe immunosuppression. Four more cases involved other patients being treated with the drug, and 2 patients were not on the drug.In view of the findings, the WHO urged clinicians to watch for resistance in:Patients with severely compromised or suppressed immune systems who have prolonged H1N1 illness and have received oseltamivir (especially if for a long time) but still have evidence of viral replicationPeople who receive preventive oseltamivir after exposure to another infected person but then get sick anyway”In both of these clinical situations, health care staff should respond with a high level of suspicion that oseltamivir resistance has developed,” the WHO said. “Laboratory investigation should be undertaken to determine whether resistant virus is present, and appropriate infection control measures should be implemented or reinforced to prevent spread of the resistant virus.”The agency also recommended conducting epidemiologic investigations in such situations to find out if a resistant virus has spread to anyone else.Person-to-person transmission of resistant H1N1 viruses has not yet been clearly shown, the WHO said. Local transmission may have occurred in some situations, but it didn’t lead to ongoing or wider transmission.The agency also said the resistant viruses do not seem to cause different or more severe symptoms. Except for immunocompromised patients, those infected with resistant viruses have had typical flu cases.The WHO does not generally recommend using oseltamivir to prevent H1N1 illness, today’s statement noted. For people who have been exposed and are at risk for a severe case, an alternative is close monitoring and early treatment if symptoms develop.In August the agency recommended against antiviral treatment for previously healthy people with uncomplicated H1N1 cases. It stressed prompt antiviral treatment for those with severe illness, pregnant women, and people with conditions such as asthma, obesity, or diabetes.See also: Sep 25 WHO statement on antivirals and resistancehttp://www.who.int/csr/disease/swineflu/notes/h1n1_antiviral_use_20090925/en/index.htmlAug 21 CIDRAP News story “WHO: In treating H1N1, save antivirals for high-risk cases”last_img read more

Posted by: | Posted on: October 20, 2020

Left keeps chipping away at our traditions

first_imgCategories: Letters to the Editor, OpinionI see in the news that riders in Bill de Blasio’s New York City subway will no longer be addressed on the PA system as “Ladies and Gentlemen,” but as “Passengers.” Another small civility down the memory hole. Since the ‘60s, the cultural Marxists have chipped away at all forms of tradition, however small. But these things accumulate.The egalitarians are relentless. It’s getting harder and harder to remain optimistic that normal people will finally run the leftists back to their faculty lounges and sit-ins, but I’m still hopeful. David VinceletteDelansonMore from The Daily Gazette:EDITORIAL: Urgent: Today is the last day to complete the censusFoss: Should main downtown branch of the Schenectady County Public Library reopen?EDITORIAL: Beware of voter intimidationEDITORIAL: Find a way to get family members into nursing homesEDITORIAL: Thruway tax unfair to working motoristslast_img read more

Posted by: | Posted on: October 19, 2020

Big fall in COVID-19 deaths in France

first_imgWith the country’s health system still under strain, Prime Minister Edouard Philippe will set out his strategy for ending the lockdown before parliament on Tuesday.Ministers have identified 17 priorities for gradually bringing the country out of eight weeks of confinement in a “controlled, progressive” manner from May 11.Schools in some areas are expected to reopen, with companies returning to work and public transport going back to a more normal timetable as a testing system and support for the elderly are put into place.  The numbers of COVID-19 victims in intensive care also dropped, but only slightly, to 4,682. But officials said they were worried by an increase in critically ill patients suffering from other conditions.More than 7,553 people were in intensive care units in France on Sunday — 50 percent more than the country’s total capacity before the epidemic struck. Overall, 28,217 people are being treated in hospital for the virus.  France reported a big fall in its coronavirus toll on Sunday, with 242 deaths in 24 hours, a drop of more than a third on the previous day.The epidemic has now claimed 22,856 lives in the country since the beginning of March, health officials said. The number of deaths in hospitals — 152 — was the lowest daily toll in five weeks, they said, while 90 people died in nursing and care homes.center_img Topics :last_img read more

Posted by: | Posted on: September 17, 2020

Syracuse-Georgetown reaches new heights, tensions flare in 1984 Big East championship

first_img Facebook Twitter Google+ Related Stories Otto-matic: Star forward Porter has carried Georgetown on the offensive end this yearOn the block: Assessing how Syracuse matches up with Georgetown ahead of last Big East duel in the DomeUnrivaled stars: All-time lineup of Syracuse-Georgetown rivalryClassic clashes: Five games that defined the Syracuse-Georgetown rivalry Sonny Spera labeled it “Hoya Paranoia.” Rafael Addison said they were “like the Oakland Raiders of college basketball.” Andre Hawkins coined it a “Georgetown-against-the-world mentality.”All three had a different, nasty, spiteful term to describe the tough-nosed style of basketball that defined Georgetown in the 1980s, but all of their callous accusations merged at a harsh consensus: The Hoyas were a dirty basketball team.“The whole ‘Hoya Paranoia’ thing, I think they just fed off that,” Spera said.” I think they just liked to be the dark side of the force. Good versus evil. I think they didn’t mind playing the bad boy role. They loved it.”That blood-bath, no-mercy, utter-hatred mentality bubbled to an all-time high in the Big East tournament on March 10, 1984, when Syracuse and Georgetown tussled in the championship finale. With four minutes remaining, a game already doused with animosity turned brutal, as Georgetown big man Michael Graham took a left-handed swipe at Syracuse forward Andre Hawkins’ face. Referee Dick “Froggy” Paparo initially ejected Graham, but after discussing the situation with coaches Jim Boeheim and John Thompson, the officiating crew decided to reverse the call. Graham stayed in the game and fueled Georgetown to a win as part of a legendary kerfuffle that epitomizes the SU-Georgetown rivalry.“You go to Syracuse, you have a friend at Syracuse, you even have a friend of a friend of a friend who goes to Syracuse, you just hate Georgetown,” Spera said. “It’s as simple as that.”AdvertisementThis is placeholder textLate in the second half, that hatred reached new heights. Syracuse was up four points and a Big East championship was on the horizon. Then, chaos ensued.Graham attempted a reverse layup in traffic that skimmed off of the backboard. Hawkins and Graham grappled for possession. Eventually, Hawkins snatched the ball away and fell to the floor. As he took the tumble, Graham swatted at him, barely missing the 6-foot-6 forward’s head.“He took a huge swing at him,” Spera said. “He took a roundhouse, left-hand, all out punch, but he didn’t hit him. … It’s just a punk move.”Paparo sprinted to the scene of the crime with a jolt in his step, ready to make a pivotal call. He signaled that Hawkins was ejected, jerking his hand toward the locker room. “He’s out! He’s out! He’s out!” Spera recalls Paparo shouting.But after the refs convened and reached a verdict, Paparo trotted to the sideline to discuss the matter with Boeheim and Thompson. He reversed the call and Graham, who Spera called a “loose cannon,” stayed in the game.That meant Syracuse only got two shots, instead of two additional technical foul shots and the ball. In a potentially pivotal twist that could have ignited SU to a victory, just the opposite happened.Spera doesn’t know why the officials changed the call, but he speculates it was due to Georgetown’s intimidation factor, particularly that of the 6-foot-10, 269-pound behemoth Thompson, who Spera said had his way with Paparo.Graham had a reputation as “the enforcer.” Addison said he epitomized the physical mentality that defined Georgetown during those years.“Put it this way: I wasn’t surprised that Michael Graham tried something like that,” Addison said. “I would have been more surprised if somebody fell down and he helped them up.”Hawkins said he had no idea Graham swatted his fist in his direction until after the game when he watched it on replay. He fell down and was focused on not traveling, his back turned when the punch came.“If you watch the video, it shows that he took a swing at me, but he never connected,” Hawkins said. “But he did take the swing, which means he should have been ejected, as far as I know.”But he wasn’t. Hawkins fouled out a minute later as Georgetown sent the game into overtime, eventually coming away with the momentous win. Carried by Patrick Ewing, the Hoyas went on to win the national championship.Spera said he remembers the brouhaha clearly, but he doesn’t remember much about Georgetown’s late-game push after the bedlam ensued.“How about that for selective memory?” Spera said, laughing. “The details get a little fuzzy after that.”Boeheim was infuriated after the game, pushing a chair in disgust in a postgame press conference.“Today,” Boeheim said, still bewildered and befuddled by the reversed call, “the best team didn’t win.” Commentscenter_img Published on February 22, 2013 at 2:25 am Contact Trevor: tbhass@syr.edu | @TrevorHasslast_img read more